2) Which operation will you perform first to solve the expression 4times 16^wedge 3+10 4times 16 16^wedge 3 3+10

To solve the expression $4 \times 16^3 + 10$, we need to follow the order of operations, often remembered by the acronym PEMDAS (Parentheses, Exponents, Multiplication and Division (from left to right), Addition and Subtraction (from left to right)).

The expression is:
$$4 \times 16^3 + 10$$

1. **Exponents $16^3$.
$$16^3 = 16 \times 16 \times 16 = 4096$$

2. **Multiplication**: Multiply the result by 4.
$$4 \times 4096 = 16384$$

3. **Addition**: Add 10 to the result.
$$16384 + 10 = 16394$$

So, the correct operation to perform first is $16^3$.

Therefore, the correct answer is:
$$16^3$$